U+2CE9 Coptic Symbol Khi Ro

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The Chi Rho (☧, English pronunciation ; also known as chrismon) is one of the earliest forms of the Christogram, formed by superimposing the first two (capital) letters—chi and rho (ΧΡ)—of the Greek ΧΡΙΣΤΟΣ (rom: Christos) in such a way that the vertical stroke of the rho intersects the center of the chi.

The Chi-Rho symbol was used by the Roman Emperor Constantine the Great (r. 306–337 AD) as part of a military standard (vexillum). Constantine's standard was known as the Labarum. Early symbols similar to the Chi Rho were the Staurogram () and the IX monogram ().

In pre-Christian times, the Chi-Rho symbol was also used to mark a particularly valuable or relevant passage in the margin of a page, abbreviating chrēston (good). Some coins of Ptolemy III Euergetes (r. 246–222 BC) were marked with a Chi-Rho.

Although formed of Greek characters, the device (or its separate parts) is frequently found serving as an abbreviation in Latin text, with endings added appropriate to a Latin noun, thus XPo, signifying Christo, "to Christ", the dative form of Christus, or χρ̅icola, signifying Christicola, "Christian", in the Latin lyrics of Sumer is icumen in.